In this scenario, colchicine has been postulated as a potential effective drug for these patients. This is a tricyclic alkaloid (C22H25NO) extracted from Colchicum autumnale that has historically been used for the gout treatment. It was first recommended for the treatment of gout by Alexander of Tralles in the 6th century BC. Colchicine is a powerful anti-inflammatory drug that acts by inhibiting the polymerization of tubulin with an effect on the inflammasome and pro-inflammatory mediators. Consequently, it was thought that it could be useful in the control of the inflammatory complications of COVID-19.