The 1950s may be considered the birth year of controlled release medication delivery. In 1952, the Spansule technique was created to deliver a medication for 12 hours. When compared to taking a medication every 6 or 8 hours, twice-daily formulations were revolutionary in terms of increasing patient compliance and convenience. Since then, developments in drug delivery technology have produced a wide range of formulations and equipment for boosting treatment effectiveness, lowering adverse effects, and boosting patient compliance. The purpose of targeted drug delivery is to deliver the provided medicine to the target areas as much as possible, while minimising the drug distribution to any non-target organs. Over the past two decades, nanotechnology-based delivery systems have progressed explosively.